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Scientific Data Analysis

End-to-end support for experimental neuroscience: from reliable data acquisition and synchronization to robust preprocessing, analysis, and reproducible publication. We focus on data quality and validity—not just code—so that scientific results are trustworthy.

15 project examples
4 research stages covered
Neuroscience-focused solutions
Immediate impact delivery
Scientific Data Analysis

Neuroscience Experiment Support Project Examples

Real challenges and collaborative solutions from neuroscience research labs. Each project demonstrates targeted expertise in action.

Covering all research stages:   Data Acquisition Data Processing Data Publication Data Analysis

Reducing 50 Hz Noise
Data Acquisition

Troubleshooting grounding, shielding, and power rail separation to eliminate line-frequency artifacts.

Multi-Camera Sync Setup
Data Acquisition

Designing timestamped multi-camera rigs with synchronized acquisition for downstream alignment.

Real-Time Data Logging Integration
Data Acquisition

Building integrations to synchronize multiple sensors with precise time bases during live experiments.

Preprocessing Calcium Imaging Data
Data Processing

Converting vendor formats, downsampling, and spatial filtering to prepare for motion correction and segmentation.

Reproducible Figures (fUSI / Imaging)
Data Publication

Translating Matlab pipelines to Python to reproduce publication-quality figures with versioned environments.

Predictive Modeling of Behavior
Data Analysis

Structuring trial data, applying smoothing, and validating predictive models with interpretable diagnostics.

Preprocessing Calcium Imaging Data
Data Processing

Outlined steps to convert Inscopix image files to TIFF, then downsample and spatial-filter them, easing the motion correction process.

Workshop: Handling Large Imaging Datasets
Data Processing

A day-long event teaching best practices for chunking data, partial reads, and naive parallel loops on local machines.

Modeling Periodic Neural Data
Data Analysis

Transitioned from a von Mises distribution to a Gaussian Mixture Model to capture asymmetric periodic neural responses.

Inception Loop for MEI Generation
Data Analysis

Implemented a deep learning pipeline to predict neural responses to natural images and generate Most Exciting Images (MEIs).

Wald's Test Implementation in R
Data Analysis

Assisted in implementing Wald's test in R for rapid hypothesis testing on biological data ahead of a key meeting.

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Why Scientific Data Quality Matters

The validity of neuroscience research depends fundamentally on data quality—not just the questions you ask or the statistical methods you apply, but whether the measurements themselves are reliable, interpretable, and traceable from acquisition through publication. Yet technical aspects of experimental workflows often receive less attention than they deserve, becoming bottlenecks that delay discovery, compromise reproducibility, or undermine confidence in results.

Good experimental support means having someone who cares deeply about the technical soundness of your data pipeline, understands the unique constraints of neuroscience research, and can work alongside your team to build infrastructure that serves science rather than fighting against it.

What We Mean by Experimental Support

Experimental neuroscience generates increasingly complex data—multi-site electrophysiology, high-speed imaging, behavioral tracking, optogenetic stimulation—all synchronized across multiple systems with different clocks, file formats, and quality metrics. Managing this complexity well requires expertise that spans hardware integration, signal processing, software engineering, and domain knowledge of what matters scientifically.

We provide domain-aware technical support across the full experimental lifecycle:

Data Acquisition: We help design and troubleshoot acquisition systems that prioritize signal quality, proper synchronization, and metadata capture. This includes addressing grounding and noise issues, configuring multi-camera setups with reliable timestamps, integrating real-time sensor logging, and ensuring that critical experimental parameters are recorded alongside raw data—not lost in lab notebook margins.

Preprocessing and Quality Assurance: Raw data rarely arrives analysis-ready. We work with you to establish preprocessing pipelines that are transparent, reproducible, and appropriate for your data type—whether that’s motion correction for calcium imaging, artifact removal for electrophysiology, or behavioral video analysis. Equally important, we help implement quality checks that catch problems early, before they propagate through analysis and into figures.

Analysis and Modeling: We support the development of analysis workflows that are scientifically sound, computationally efficient, and maintainable over time. This ranges from helping select appropriate statistical models for neural data to implementing custom pipelines for specialized analyses like MEI generation or periodic response modeling. The goal is code that you understand, can modify, and can defend in reviews.

Reproducible Publication: Making your work reproducible means more than sharing data—it means creating analysis pipelines that others can actually run and understand. We help translate your analysis workflows into reproducible formats, migrate code to open-source tools when needed, generate publication-quality figures with versioned environments, and prepare datasets for sharing in ways that meet both journal requirements and FAIR principles.

Why Bring in Outside Expertise

Research groups rarely have dedicated technical staff with expertise spanning experimental hardware, signal processing, software development, and neuroscience domain knowledge. Graduate students and postdocs are brilliant scientists, but they’re often learning these technical skills on the fly while simultaneously trying to complete experiments and write papers.

Having someone who specializes in these technical aspects—who stays current with best practices, has seen similar problems across multiple labs, and can dedicate focused time to infrastructure rather than squeezing it between experiments—can transform research velocity and quality. More importantly, working collaboratively means your team learns sustainable practices rather than receiving black-box solutions.

We believe that neuroscience research benefits when technical quality is treated as a first-class concern, not an afterthought. Good data infrastructure feels invisible when it works well: experiments run smoothly, analysis is reproducible, collaborations are easier, and you spend more time on science and less time fighting with technical problems.

If your research involves experimental neuroscience data—whether you’re troubleshooting acquisition issues, building preprocessing pipelines, or preparing for publication—we’re here to help ensure the technical aspects of your work are as sound as the scientific questions driving them.

Let's Work Together!

Nicholas A. Del Grosso
Nicholas A. Del Grosso

delgrosso.nick@uni-bonn.de

About Nicholas
Sangeetha Nandakumar
Sangeetha Nandakumar

nandakum@uni-bonn.de

About Sangeetha
Ole Bialas
Ole Bialas

bialas@uni-bonn.de

About Ole
Atle E. Rimehaug
Atle E. Rimehaug

rimehaug@uni-bonn.de

About Atle
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